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This episode explores how and why hemoglobin's function emerges from its structure, which makes it a critical component in the oxygen distribution chain. We also discuss the lungs, why VO2max isn't related to hematocrit, and vascular capacity for blood storage before diving into a classic phlebotomy study that ends with a question mark that hints at the central importance of the heart.
Show Notes Blood value correlations with vo2max, Figure 1 https://pubmed.ncbi.nlm.nih.gov/30549016/ Effects of detraining on cardiovascular responses to exercise: role of blood volume https://journals.physiology.org/doi/pdf/10.1152/jappl.1986.60.1.95
1 Comment
8/12/2020 01:58:38 pm
Just to add one more factor to the first table: Hemoglobin A1c (glycosylated hemoglobin) also has a left-shifted dissociation curve. Thus, with diabetes mellitus, as Hb A1c concentration increases with poor blood glucose control, the hemogolbin dissociation curve is shifted somewhat to the left.
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