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Ten Minute Tips #35: Higher FTP vs Longer TTE

2/19/2024

Empirical Cycling Podcast · Ten Minute Tips #35: Higher FTP vs Longer TTE

This is an in depth discussion on the upsides and downsides of always training to raise FTP vs holding it longer. After defining terms, we discuss the training required, adaptation timelines, fatigue, long term development, plus coaching and event specific considerations. We also consider a few counterpoints for each kind of training, individual response and needs, whether or not this is an actual debate, and answer your listener questions.

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Watts Doc #48: How PGC-1ɑ Does and Doesn't Live Up To The Hype

2/11/2024

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Empirical Cycling Podcast · Watts Doc #48: How PGC-1ɑ Does and Doesn't Live Up To The Hype

This episode goes deep into the integral role that PGC-1ɑ plays in turning exercise signals into aerobic adaptation and improved endurance performance. We then dig into the very surprising results of studies that selectively knock out the PGC-1ɑ gene. Finally, we discuss potential uses of this knowledge for training applications and interpreting the literature, the actual best ways to know if your training (or training "hack") is working, and answering your listener questions.

Show Notes
Three PGC-1ɑ reviews:
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
Transcriptional integration of mitochondrial biogenesis
Mitochondrial regulator PGC-1a—Modulating the modulator - PMC

Knockout studies:
PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis
PGC-1α is Dispensable for Exercise-Induced Mitochondrial Biogenesis in Skeletal Muscle
Adult expression of PGC-1α and -1β in skeletal muscle is not required for endurance exercise-induced enhancement of exercise capacity

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Ten Minute Tips #35: Higher FTP vs Longer TTE

Watts Doc #48: How PGC-1ɑ Does and Doesn't Live Up To The Hype

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