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After some background information on what redox state means for exercise and your mitochondria, we look at some experiments linking various intensities of exercise to adaptations. Then we look at where these signals overlap with dieting and rest, and tie these into advice and realistic expectations for training, recovery, and nutrition. We also answer your listener questions on RED-S, measuring recovery, exercise intensity, and more.
Show Notes Review papers on fluorescence measurement and redox adaptations Mitochondrial function in vivo evaluated by NADH fluorescence: from animal models to human studies NAD+/NADH and skeletal muscle mitochondrial adaptations to exercise Main podcast study Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle Frequently referenced study linking SIRT activation to mitochondrial biogenesis (not mentioned in episode) Sirtuin 1 (SIRT1) Deacetylase Activity Is Not Required for Mitochondrial Biogenesis or Peroxisome Proliferator-activated Receptor-γ Coactivator-1α (PGC-1α) Deacetylation following Endurance Exercise*
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When it comes to glycogen, does "train low" actually work? Rory joints to co-host as we examine and dissect the existing literature, and explore the limits of knowledge on p38 MAPK signaling as it relates to aerobic performance. We go through Kolie's coaching experience with these protocols, compare to existing recommendations, discuss why you should always check someone's references, and answer your listener questions.
Show Notes Exercise Stimulates Pgc-1α Transcription in Skeletal Muscle through Activation of the p38 MAPK Pathway Acute signalling responses to intense endurance training commenced with low or normal muscle glycogen Skeletal muscle adaptation and performance responses to once a day versus twice every second day endurance training regimens
This is a conversation between Kolie and epidemiologist Dr. Traci Carson, RDN and cycling coach Dr. Namrita Brooke, and MD and cycling coach Dr. Fabiano Araujo, in light of the Kristen Faulkner disqualification at Strade Bianche for wearing a continuous glucose monitor. We look at topics of whether CGMs actually confer a performance advantage, where their true utility lies, their shortcomings, thoughts on the UCI rules and Faulkner's DQ and the role of a team or dietitian, and health issues surrounding endurance athletes like RED-S and LEA.
Show Notes Traci Carson Namrita Brooke Fabiano Araujo Rouleur article The Use of Continuous Glucose Monitors in Sport Periodized Nutrition by Prediction of Glycemic Responses
This is an in-depth discussion on weight loss diets for endurance athletes, with Dr. Namrita Brooke. The conversation includes guidelines on finding the right starting point and how to adjust energy intake, avoiding crash diets, performance expectations and markers when dieting, the effect of off-bike activity, and reasonable loss rates. We also discuss energy balance vs hormones, demonizing food groups and the role of each macronutrient, the best times of year to lose weight, and your listener questions on diet aids, recomp diets, calorie estimates from wearables, finding a good performance dietitian, and more.
Show Notes Inside Sports Nutrition Instagram Namrita's website [email protected]
This discussion with Namrita (PhD, RDN) centers on ride food questions like how much, when, how to adjust for early rides, races, and if protein and fat is necessary. Additional side quests include the glucose-fructose ratio, how important ride food is in the context of the day, gastric emptying rate, the effects of caffeine, solid vs liquid food, and many others.
Show Notes [email protected] Namrita's Instagram Inside Sports Nutrition Caffeine Ingestion With or Without Low-Dose Carbohydrate Improves Exercise Tolerance in Sedentary Adults 13C-glucose-fructose labelling reveals comparable exogenous CHO oxidation during exercise when consuming 120 g/h in fluid, gel, jelly chew or co-ingestion Feeding Tolerance, Glucose Availability, and Whole-Body Total Carbohydrate and Fat Oxidation in Male Endurance and Ultra-Endurance Runners in Response to Prolonged Exercise, Consuming a Habitual Mixed Macronutrient Diet and Carbohydrate Feeding During Exercise Effects of supplementing with an 18% carbohydrate-hydrogel drink versus a placebo during whole-body exercise in −5 °C with elite cross-country ski athletes: a crossover study
Tim Podlogar, nutritionist for Bora-Hansgrohe and research fellow at the University of Birmingham, joins Kolie for a conversation. Just a few of the topics covered are what makes Slovenian riders so good, what lab tests are useful and for whom, low-carb rides, and why substrate use is not adaptation. Nutrition topics include fructose, "fat loading," the role of supplements like creatine, bicarbonate, and beta-alanine. Also discussed are things like responsibility for our media's influence, and the pressures, dangers, and nuances of MDPI and scientific publication.
Show Notes Tim's Instagram Tim's Twitter Tim's publications |
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